CORDIS Project
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This project explores the genetic mechanisms behind eye development using zebrafish. It focuses on the role of the transcription factor Six3 in preventing birth defects related to eye formation.
Anophthalmia and microphthalmia, birth defects that are important causes of childhood blindness, often arise as a result of abnormal development of eye progenitors in the eye field during early embryogenesis.
The molecular genetic mechanisms that underlie eye progenitor development in the eye field are not well understood.
This proposal aims to identify cellular, molecular and genetic mechanisms of eye progenitor development during the eye field stage using zebrafish as a model organism.
We will…
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