CORDIS Project
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The BioCompatibility Innovation project aims to improve bioprosthetic heart valves by developing a treatment to inactivate harmful xenoantigens. This innovation seeks to reduce calcification and enhance the durability of heart valve replacements, addressing significant health concerns.
Heart valve disease is one of the main causes of morbidity and mortality worldwide.
In 2017 around 400.000 patients underwent heart valve replacement.
Mechanical (MHVs) and Bioprosthetic (BHVs) Heart Valves are the most used substitutes.
However, the former have problems related to their thrombogenicity, the latter durability issues that limit their use.Recently an alarming correlation between the presence of the alpha-Gal epitope and a premature BHVs degeneracy was reported.BioCompatibility I…
BIOCOMPATIBILITY INNOVATION SRL
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