CORDIS Project
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This project aims to develop a targeted therapy for Non-alcoholic Steatohepatitis (NASH) by blocking a specific platelet surface molecule. The approach seeks to prevent liver disease progression without the side effects of traditional treatments.
Changes in life-style and nutrition have increased the incidence of obesity/overweight and metabolic syndrome resulting in a pathology called Non-alcoholic fatty liver disease (NAFLD).
Currently, 130 million people in Western countries have NAFLD and this number is constantly increasing. A significant number of patients develop non-alcoholic steatohepatitis (NASH), fibrosis and subsequently liver cancer.
At the same time no efficient therapeutics exist to treat NASH or NASH-liver cancer transiti…
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
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