CORDIS Project
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This project investigates the behavior of CD8+ T cells in the liver, focusing on their migration and activation in response to infections and tumors. By utilizing advanced imaging techniques, the research aims to uncover the dynamics of T cell interactions in the liver, potentially leading to better treatments for live…
CD8+ T cells have a key role in eliminating intracellular pathogens and tumors that affect the liver.
The protective capacity of these cells relies on their ability to migrate to and traffic within the liver, recognize pathogen- or tumor-derived antigens, get activated and deploy effector functions.
While some of the rules that characterize CD8+ T cell behavior in the infected and cancerous liver have been characterized at the population level, we have only limited knowledge of the precise dynam…
OSPEDALE SAN RAFFAELE SRL
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