CORDIS Project
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This project investigates how messenger RNA (mRNA) is processed in human cells to determine its fate as either functional or faulty. By using advanced imaging techniques, it aims to visualize the complex interactions involved in mRNA splicing, packaging, and degradation, enhancing our understanding of gene expression r…
Messenger RNA (mRNA) is critical for transferring information from DNA to protein, a process that requires a series of tightly orchestrated steps.
During these steps, mRNAs are classified as either functional or faulty, and directed towards biogenesis or degradation.
This ensures the efficient and faithful expression of protein-coding genes.
Yet, the mechanisms that decide the fate of mRNAs remain unclear.
Prior work and our preliminary data show that RNA splicing plays a critical role in making…
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