CORDIS Project
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This project focuses on developing new drugs for prostate cancer by targeting a specific protein binding site, the activation function 2 site, to overcome resistance associated with traditional treatments. Utilizing advanced computational drug discovery techniques, the goal is to design and optimize small molecules tha…
One of the traditional approaches for the treatment of prostate cancer is the administration of steroid-derived Androgen Receptor (AR) antagonists.
These treatments show significant side effects due to their high dosing requirements.
In a novel intervention approach Molecular Design Group (Trinity College Dublin), has used a variety of computational drug discovery techniques to analyse a recently identified, non-steroid AR protein binding site, termed the activation function 2 (AF2) site.
The g…
THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
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