CORDIS Project
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This project explores the biophysical mechanisms of cell polarity during early embryo development using C. elegans as a model organism. It aims to develop new simulation methods to better understand how cells establish their orientation and function in multicellular structures.
All living organisms emerge from a single cell, the zygote.
In early embryo development of animals, the interplay of cell surface dynamics, polarity proteins and intracellular flows forms distinct polarity domains, which the cell uses to specify the fate of its daughter cells. A classical biological model to learn how animal cells polarise is the 1-mm long C. elegans roundworm.
Establishment of cell polarity in the C. elegans zygote is well studied, yet the biophysical mechanisms controlling cel…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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