CORDIS Project
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This project investigates the role of fibroblast cells in vascular ageing and their contribution to cardiovascular diseases. By utilizing advanced techniques, the research aims to identify distinct fibroblast subsets and their functions, ultimately seeking to uncover potential therapeutic targets for vascular dysfuncti…
Vascular ageing is a major cause of cardiovascular disease, but effective treatment for fibrotic effects of vascular ageing is lacking.
Recent studies show that fibroblasts exhibit physiological and pathological functions beyond their central role in fibrosis.
Supporting this view of the field, the host lab recently showed great intra-vascular fibroblast plasticity in atherosclerotic and ageing murine arteries.
We hypothesize that vascular dysfunction and fibrosis with ageing originate from alte…
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