CORDIS Project
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This project aims to develop animal models that mimic the early stages of cancer metastasis, specifically focusing on the transition of epithelial cells to invasive cells. By understanding the genetic changes involved in this process, the research seeks to identify new therapeutic targets for preventing or treating met…
Metastasis is the process whereby a primary tumor (usually highly malignant in nature) spreads to distant locations in the body.
Understanding step-by-step how particular confined tumors acquire invasiveness and/or spreading potential is a scientific challenge that can help us to develop new strategies for metastatic cancer prevention or treatment.
In mouse models and in humans, the inactivation of the E-cadherin gene and the activation of genes of the SNAIL family are markers of the initiation…
UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE
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