CORDIS Project
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The project aims to create an advanced data analysis tool for Isothermal Titration Calorimetry, enabling researchers to develop and share binding models for studying molecular interactions. It will focus on tau-tubulin interactions, relevant to cancer and neurodegenerative diseases.
Isothermal titration calorimetry (ITC) is a powerful biophysical method to study intermolecular interaction that has become widely used due to its technological advances.
It enables the determination of all thermodynamical parameters of interaction after a single one-hour experiment.
The key step of experimental data analysis is the fitting of obtained data using an appropriate binding model.
Unfortunately, the limited set of models offered by manufacturers does not allow the full use of ITC for…
UNIVERSITE D'AIX MARSEILLE
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