CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the role of sodium leak channels in neuronal excitability by studying patient mutations in a human stem cell model. It aims to understand the effects of these mutations on neurological functions and identify potential drug therapies to treat related disorders.
The resting membrane potential of a cell is a crucial element of signal transduction across cell membranes and temporary changes are the basis of neuronal excitability.
The key ions in the process are unequally distributed intra- and extracellularly and ion channels are regulating the transport.
One of the main ions involved in this process are sodium ions.
The depolarizing sodium influx on the resting membrane potential is primarily mediated by the sodium leak channel (NALCN).
The neurological…
KOBENHAVNS UNIVERSITET
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
Guests see up to 5 keywords.
