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The Foldappi project explores the use of aromatic amide foldamers to inhibit protein-protein interactions, specifically targeting the interaction between interleukin 4 and its receptor. By developing synthetic methods and strategies for foldamer design, the project aims to contribute to treatments for immune-related di…
The Foldappi proposal aims to investigate the potential of aromatic amide Foldamers to disrupt protein-protein interactions.
The scientific goals of the project include: 1. development of synthetic methods to build foldamers with different R-group chemistries 2. development of strategies to target foldamers to protein surfaces 3. measuring in vitro properties of foldamer(s) to assess ADME profiles of these molecules In this proposal we propose to explore the use of quinoline-derived aromatic a…
UNIVERSITE DE BORDEAUX
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
France, TALENCE
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
Belgium, Bruxelles / Brussel
Type: Company (for-profit)
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: No
Germany, Wuerzburg
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Belgium, BRUXELLES
Type: Company (for-profit)
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
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