CORDIS Project
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This project investigates how maternal obesity affects the development of the hypothalamus in offspring, focusing on molecular and cellular changes that may impair metabolic control. By analyzing gene expression and neuronal circuitry in mice, it aims to uncover the long-term impacts of maternal diet on brain function…
Evolutionary success drives continuous human adaptation. A pervasive challenge is the substantial change in the composition and nutritional value of diets available.
This is particularly relevant for child-bearing women because metabolic bias through diet composition can adversely affects pregnancy outcomes.
Even though clinical and experimental studies correlate maternal obesity during pregnancy (affecting ~30% world-wide) with congenital metabolic illnesses, a causal relationship between mater…
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