CORDIS Project
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This project investigates how microtubule asters move and position within cells during development. By studying the mechanics of these structures in sea urchin embryos, it aims to understand the forces driving their motion and organization.
Cells must move and position internal components to perform their function.
We here focus on the physical designs which allow microtubule (MT) asters to exert forces in order to move and position themselves in vivo.
These are arrays of MTs radiating from the centrosome, which fill up large portions of cells.
They orchestrate nuclear positioning and spindle orientation for polarity, division and development.
Forces that move asters are generated at nanometer and second scales by MT-associated mot…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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