CORDIS Project
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This project introduces Self-configurable, Proximity Enabling Devices (SPEDs) for oral delivery of protein and peptide drugs. These devices unfold in the gut, embed in mucus, and align with the intestinal wall to enhance drug absorption and retention, while also enabling studies on drug delivery mechanisms and micromot…
Oral delivery of protein/peptide drugs is extremely challenging and the majority of research in the field is based on exploring new formulations, for instance using permeation enhancers.
In recent years, some research has been done on ingestible devices for internal injections.
Here I propose an entirely new approach based on what we have named ‘Self-configurable, Proximity Enabling Devices’ (SPEDs).
The idea is that these devices (the simplest ones will be rolled-up foils) will unfold in the gu…
TECHNICAL UNIVERSITY OF DENMARK DTU
DANMARKS TEKNISKE UNIVERSITET
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