CORDIS Project
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This project investigates the role of calcium-independent phospholipase A2 isoforms in calcium entry and muscle cell death in Duchenne muscular dystrophy. By analyzing muscle fibers from affected individuals and animal models, the research aims to identify potential therapeutic targets to mitigate symptoms of this seve…
The applicant proposes a 2-year project to be performed under the supervision of Prof Bernheim, a neuromuscular disease expert at the University of Geneva.
The goal of this project is to determine the role of isoforms of calcium-independent isoform phospholipase A2 (iPLA2) in cytosolic calcium entry and muscle cell death during Duchenne muscular dystrophy (DMD).DMD is the most severe case of muscle-wasting diseases of the muscular dystrophies family.
It affects 1 in 3500 children, and is caused…
UNIVERSITE DE GENEVE
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