CORDIS Project
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This project explores the role of genetic variations in RasGRP1 in autoimmune diseases, focusing on how these variations affect lymphocyte activity. The research aims to develop targeted therapies by understanding the underlying mechanisms of autoimmunity.
Autoimmunity is caused by chronic inflammation mediated by T- and B-lymphocytes.
Thus far, treatment of autoimmunity consists of general immune suppressants, causing unwarranted side effects, without curing disease.
Therefore, the need for a specific treatment targeting the cause of disease is growing.
In this fellowship will focus on elucidating how SNPs (single nucleotide polymorphisms) in RasGRP1 play a role in aberrant lymphocyte activity in patients with autoimmunity.
RasGRP1 is critical in…
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
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