CORDIS Project
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This project explores how mitochondrial adaptations in myeloid cells affect their immune functions. By investigating the organization of mitochondrial super complexes, the research aims to uncover mechanisms that could lead to new therapeutic targets for various diseases.
The emerging field of immunometabolism has a strong potential to uncover novel targets for the manipulation of immune cell function.
Myeloid cells are involved in innate and adaptive immunity and tolerance, therefore the identification of pathways that regulate their activity may have implications in many diseases.
Research in the host laboratory has focused on how sensing of innate stimuli (infections and tissue damage) lead to mitochondrial adaptations in myeloid cells.
These mitochondrial ada…
CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.)
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