CORDIS Project
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This project explores the concept of gene architecture to uncover biological functions that are not detectable through traditional methods. By creating a database and algorithm to evaluate gene architecture conservation, it aims to identify functional elements within genes, such as introns and splice junctions, that ma…
One of the fundamental principles in comparative genomics is that evolutionary conservation implies functional importance.
This principle has been used extensively in the life sciences, as a tool to detect biological functionality.
In the vast majority of studies, evolutionary conservation has been sought in three biological “entities”: sequence (actual nucleotide or amino-acid sequences, as well as sequence properties like codon usage bias, GC content, and amino-acid bias); structure (like RNA,…
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