CORDIS Project
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This project aims to develop new methods for forming carbon-carbon bonds in organic chemistry, focusing on palladium-catalyzed reactions. It seeks to enable the formation of complex molecules through innovative oxidation techniques.
The formation of new carbon-carbon bonds is of central importance in organic chemistry and a prerequisite for all life on earth.
In this context, palladium catalysed cross-couplings have emerged as exceptionally powerful and useful methods for C-C bond formation.
However, the reaction is largely limited to C(sp2)–C(sp2) bond formation.
There are very few examples of cross couplings to form C(sp2)–C(sp3) or C(sp3)–C(sp3) bonds due to inherent problems associated with transition metals.
As such a…
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