CORDIS Project
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This project focuses on stabilizing the pre-fusion form of the rabies virus glycoprotein to improve vaccine development. By utilizing computational biology and structural biology, it aims to create more effective rabies vaccines that are easier to produce and administer.
This proposal aims to stabilize the pre-fusion form of rabies virus glycoprotein (RVG), the most structurally-tractable clinically-relevant class III fusogen by combining computational biology, immunology, and structural biology.
Rabies virus is fatal; it kills 55,000 people each year and costs billions to control it in animals.
Current human rabies vaccines are cumbersome to use and prohibitively costly, thus there is demand for a new generation of rabies vaccines.
Enveloped viruses’ fusion gly…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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