CORDIS Project
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This project investigates a novel variant of a neurotrophic factor that can penetrate the blood-brain barrier to treat neurodegenerative diseases like Parkinson's and amyotrophic lateral sclerosis. The goal is to develop therapies that restore neuron function through non-invasive delivery methods.
The prevalence of neurodegenerative diseases such as Parkinson’s disease (PD) and amyotrophic lateral sclerosis (ALS) is growing rapidly due to an aging population and increased life expectancy.
Current treatments for ALS and PD only relieve symptoms and cannot stop the progression of the disease, thus there is an urgent need for new therapies.
Neurotrophic factors (NTFs) are secretary proteins that regulate the survival of neurons, neurite growth and branching.
They have been explored as novel…
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