CORDIS Project
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This project investigates how the balance between excitation and inhibition in the brain is regulated by examining the interaction of glutamatergic and GABAergic synaptic plasticity. It focuses on understanding the local effects of excitatory and inhibitory synapses on each other using advanced imaging and electrophysi…
Throughout lifetime a proper balance between excitation and inhibition is crucial for a healthy brain.
How exactly this balance between excitation and inhibition is regulated in the brain is not well understood.
One intriguing possibility is that glutamatergic and GABAergic synaptic plasticity are not regulated separately, but somehow interact to maintain this balance.
In the work proposed here we intend to examine whether plasticity of inhibitory and glutamatergic synapses interact with each ot…
UNIVERSITEIT UTRECHT
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