CORDIS Project
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This research explores the development of GABAergic inhibitory circuits in the brain, focusing on the growth and branching of interneuron neurites. It aims to identify the molecular mechanisms that shape these circuits and their implications for neurological disorders.
The appropriate wiring of neuronal circuits in mammalian brain forms the basis to generate, integrate, and process patterns of neuronal activity, which underlie perception and cognition.GABAergic inhibitory circuits consist of an array of
interneuron cell types with distinct morphology, physiological properties, and synaptic connectivity patterns, and may constitute a scaffold to organize local cortical connectivity and activity.A definite feature of GABAergic innervation is
their specific axona…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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