CORDIS Project
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This project investigates the effects of the obesity drug semaglutide on fetal development, particularly its impact on the hypothalamus, which controls food intake. It aims to understand whether exposure during pregnancy leads to metabolic issues in offspring.
Obesity and associated metabolic diseases represent a significant health challenge and financial burden worldwide.
Recently, a breakthrough has been made in the treatment of obesity with drugs such as semaglutide (Ozempic), which mimic endogenous glucagon-like peptide 1 (GLP1) action in the brain and cause weight loss via reduced food intake.
The hypothalamus is the key brain region involved in the neuronal control of food intake.
Recent research shows that perturbations to the maternal environm…
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United Kingdom, London
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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