CORDIS Project
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This project develops an automated microfluidics device to simulate digestion and intestinal absorption of orally ingested compounds. It integrates real-time monitoring and uses primary cells to create disease models, enhancing personalized medicine and understanding of gut microbiome interactions.
People can only ingest food through the oral cavity, and oral administration remains the preferred route for the delivery of drugs or dietary supplements.
However, orally ingested compounds must first survive digestion and then be absorbed at the small intestine to reach the systemic circulation.
This proposal aims to develop and fabricate the first automated microfluidics-based device for complete simulation of the processes of digestion and intestinal absorption of orally ingested bioactive co…
LABORATORIO IBERICO INTERNACIONAL DE NANOTECNOLOGIA LIN
INTERNATIONAL IBERIAN NANOTECHNOLOGY LABORATORY
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