CORDIS Project
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This project investigates the role of RNA-binding proteins in regulating B cell responses, particularly during immune reactions. By identifying these proteins, it aims to uncover new targets for treating autoimmune diseases linked to B cell dysfunction.
Antibodies secreted by B cells of the adaptive immune system establish an essential barrier against bacteria and viruses and their presence is the hallmark of protective vaccinations. B cells are licensed for their tasks during germinal center (GC) reactions and differentiation into antibody-secreting plasma cells.
Unfortunately, B cell-derived autoantibodies and proinflammatory cytokines can cause or contribute to autoimmune diseases.While major transcription factor networks regulating protecti…
KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN
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