CORDIS Project
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This project focuses on developing a new method for identifying and producing novel solid forms of drug substances, which can significantly affect their bioavailability. The approach utilizes supramolecular gels to influence crystal growth of active pharmaceutical ingredients.
The solid form of drug substances (active pharmaceutical ingredients, API) is of huge importance to the European pharmaceutical industry and the European economy, which makes tremendous investments on crystal structure calculation and empirical polymorph screening.
Different crystal forms (polymorphs, pseudopolymorphs, salts or co-crystals) have different bioavailability and solubility, and the crystal morphology significantly affects processing and tabletting behaviour.
Here, we propose to deve…
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