CORDIS Project
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This research focuses on understanding the role of estrogen in the gender gap observed in cystic fibrosis patients. By studying microRNA regulation, the project aims to enhance knowledge of inflammation in cystic fibrosis and contribute to better therapeutic strategies.
Cystic fibrosis (CF) is a hereditary disease involving a defective ion channel, resulting in altered epithelial cell function and consequent infective/inflammatory airway exacerbations.
Progressive loss of lung function is the leading cause of death in CF patients.
It is statistically noted that females have a disadvantage in survival and morbidity; this is commonly referred to as the CF gender gap.
Recent studies have implicated the female sex hormone, estrogen, in this gender gap. CF patients…
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