CORDIS Project
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This research aims to improve understanding of psychotic disorders by mapping genetic variants to specific disease mechanisms. By analyzing a large dataset, it seeks to identify genetic subtypes of psychosis and develop a classifier for patient stratification.
Psychotic disorders impose an increasing burden on the health of the European population, with an estimated five million affected individuals.
As available drugs remain ineffective for 30% of the patients and come with many secondary effects, there is urgent need to develop effective and safe therapeutic agents.
Due to the high heritability of psychotic disorders, genetics shows great potential to inform the molecular mechanisms behind their pathogenesis.
However, the information we have gathere…
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