CORDIS Project
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This project aims to explore RNA editing in mammals using advanced sequencing techniques to understand its role in disease and genome evolution. The research will identify how alterations in RNA editing levels are associated with various health conditions.
With the exception of infrequent random mutations (and immune cell receptors), it is widely believed that the genomic content should be fixed in an organism throughout its body and its lifespan.
It is therefore clear why the discovery of proteins that can edit the RNA have generated much interest.
However, only very few targets have been discover so far. I have recently made important progress in this area by developing novel methods to model and detect RNA editing in mammals.
Using a combinatio…
BAR ILAN UNIVERSITY
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