CORDIS Project
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This research project investigates the relationship between chromosome segregation and repair in eukaryotic cells, using budding yeast as a model. It aims to uncover the molecular mechanisms that ensure genome stability, which is vital for preventing diseases such as cancer and developmental disorders.
The eukaryotic genome combines a highly dynamic nature with stable transmission of genetic information from mother to daughter cells.
This is achieved by a plethora of protein networks regulating processes such as chromosome duplication, segregation and repair.
The principal aim of our research is to determine the molecular interplay between chromosome segregation and repair.
Accurate execution of these two events is crucial for the maintenance of genome stability, which in turn is essential for…
KAROLINSKA INSTITUTET
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