CORDIS Project
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This project aims to enhance the production of therapeutic proteins in plants by engineering them to produce human-like sugar structures. It focuses on transgenic maize to improve the efficacy of plant-derived pharmaceuticals.
Plant-derived pharmaceuticals (PDPs) have immense potential to address the economic and capacity limitations of current fermenter-based production technology.
Several complex multi-subunit and glycosylated proteins have been produced in transgenic plants, which are safe, convenient and cost-effective for large-scale production.
High-biomass leaf and seed crops, such as maize and tobacco, are the most widely used.
However, since most clinically-relevant recombinant proteins are glycosylated, one…
UNIVERSITAET FUER BODENKULTUR WIEN
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