CORDIS Project
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This project focuses on improving immunotherapy for glioblastoma, a challenging brain tumor, by developing a new polymer-based drug delivery system. The approach aims to enhance local treatment efficacy while minimizing systemic side effects through targeted delivery of therapeutic agents.
Research focusing on cancer immunotherapy has provided little progress toward improved survival rates for patients with glioblastoma (GBM), a poorly immunogenic tumor.
Clinical trials for GBM immunotherapy primarily focus on the systemic administration of therapeutics; however, they have shown limited therapeutic success.
The blood-brain barrier, the tumor immune microenvironment (TIME), the extracellular matrix, the highly invasive/proliferative nature of GBM, and intra- and inter-patient heter…
UNIVERSITA DEGLI STUDI DI PADOVA
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