CORDIS Project
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This project investigates the role of the Rev-erbalpha gene in regulating lipid and glucose metabolism, particularly its influence on insulin resistance and type 2 diabetes. It aims to understand how circadian rhythms affect metabolic processes, potentially leading to new treatment strategies for metabolic disorders.
The increasing incidence of obesity and type 2 diabetes is becoming a major health problem in the European Community and has a considerable economic and social cost.
There is therefore an urgent need to understand the basics of these diseases.
Physiological processes are subjected to natural daily fluctuations.
Interestingly, daily cycles in insulin secretion and glucose tolerance are lost in patients with type 2 diabetes.
There is an increased incidence of obesity, metabolic syndrome and cardio…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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