CORDIS Project
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This project explores the genetic and environmental factors influencing diabetes risk, particularly in lean individuals. It aims to study the impact of prenatal and long-term exposures on glucose metabolism, identifying biomarkers that could inform prevention and treatment strategies for diabetes.
The aim of this proposal is to make a major advance in understanding why some people develop diabetes despite relative leanness and why others maintain normal glucose levels despite obesity.
My vision is that human genetics and the ability to study humans will provide a major leap in understanding disease mechanisms.
We will use state of the art resources in genomics, metabolomics, and large human biobanks to study three stages in life that may influence predisposition to diabetes independently…
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