CORDIS Project
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This project explores the role of AMPA receptors in synaptic plasticity, focusing on the trafficking of the GluR1 subunit. Using advanced imaging techniques, it aims to uncover the molecular mechanisms regulating receptor movement and its implications for memory processes.
The spatial and temporal regulation in the composition of the postsynaptic membrane of synapses participates to the different forms of synaptic plasticity that trigger the cellular processes of memory formation, consolidation, and retrieval.
Neurotransmitter receptors move rapidly in and out of synapses by lateral diffusion.
This mobility is crucial to control the number of receptors present at a given synapse. AMPA subtype glutamate receptors mediate most excitatory transmission in the brain. T…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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