CORDIS Project
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This project focuses on developing a high-throughput analytical instrument that combines ion mobility spectrometry, cryogenic infrared spectroscopy, and mass spectrometry to analyze glycan structures. This innovative approach aims to overcome challenges in distinguishing complex glycan isomers, which are crucial for un…
Glycans, or oligosaccharides, are ubiquitous in biological systems.
Because they decorate the surface of cells, they play a key role in virtually all cellular recognition processes and are implicated in almost every major disease.
Despite their importance, the characterization of glycan primary structure lags far behind that of proteins and DNA because of their intrinsic isomeric complexity.
The isomeric nature of the monosaccharide building blocks, the stereochemistry of the glycosidic bond, t…
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
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