CORDIS Project
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The project focuses on glycosylation, the process of adding carbohydrate structures to proteins, and its implications in cancer. It aims to develop glycomimetics to modify the glycome of cancer cells, potentially enhancing their susceptibility to treatment.
Glycosylation, the expression of carbohydrate structures on proteins and lipids, is found in all the domains of life.
The collection of all glycans found on a cell is called the “glycome” which is information rich and a key player in a plethora of physiological and pathological processes.
The information that the glycome holds can be written, read and erased by glycosyltransferases, lectins and glycosidases, respectively.
The immense structural complexity and the fact that glycan biosynthesis is…
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