CORDIS Project
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This project focuses on the automated synthesis of sialylated oligosaccharides to study their role in the infection mechanisms of influenza viruses. The goal is to create glycan arrays that can help develop new diagnostics and therapeutics against influenza.
The presence of carbohydrate structures on the surface of proteins has been estimated to occur in more than 50% of eukaryotic cells, and is linked to several biological events such as cell signalling regulation, cellular differentiation and immune response.
Of the three classes of biooligomers, oligosaccharides have proven to be the most difficult to synthesize.
Studies concerning the structure and function of oligonucleotides and peptides have greatly benefited from the feasibility of conductin…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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