CORDIS Project
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This project focuses on synthesizing cyclic glycopeptides to develop novel inhibitors for protein-protein interactions, particularly targeting alpha-helices. It combines techniques from carbohydrate chemistry and molecular modeling to create bioactive compounds.
Dr.
Jarikote, an Indian national who has recently completed his PhD in Germany and is currently working with Prof.
Dr.
Paul Murphy.
It is proposed that Dr.
Jarikote will work on solid phase synthesis of cyclic glycopeptides and their biophysical characterization with a view to generating novel inhibitors of protein-protein interactions, in particular those that involve a-helices.
He will also receive training in carbohydrate chemistry, scaffolds, NMR and molecular modelling and their application…
UNIVERSITY OF GALWAY
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