CORDIS Project
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This project investigates the role of glycans in cellular functions using organotypic tissue models and gene editing. It aims to uncover how glycosylation affects epithelial homeostasis, protein functions, and host-pathogen interactions, addressing the complexity of glycan analysis.
Glycans decorate most proteins, cover cell membranes, and represent one of the four building blocks of life, together with nucleic acids, lipids, and amino acids.
Yet, our understanding of how glycans influence the life of cells and organisms is limited, and only few functions have been molecularly dissected.
Glycans present a huge structural diversity with species and cell- type specificity that underlie specific biological functions.
However, more than half a century of research has been sever…
KOBENHAVNS UNIVERSITET
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