CORDIS Project
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This project focuses on developing a novel nanoplatform that combines gold nanoparticles with insulin to enhance the delivery of therapeutic agents for cancer treatment. It aims to improve the efficacy of antibody-drug conjugates for challenging cancers like triple negative breast cancer.
Antibody-drug conjugates (ADCs) have emerged as promising therapies by combining the precision targeting abilities of antibodies with the potency of chemotherapy drugs, to directly attack cancer cells and minimize damage to healthy tissue.
However, approved ADCs show low efficacies in treating solid tumours, due to inherent challenges.
These include design challenges, which limit the drug-antibody ratio and the ability to integrate multiple drug types, and delivery challenges, in which pharmacok…
BAR ILAN UNIVERSITY
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