CORDIS Project
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GRACE investigates the effects of glucocorticoids, hormones released in response to stress, on health and aging. The project aims to differentiate beneficial effects of glucocorticoids from harmful ones, particularly in the context of dietary interventions like caloric restriction, to identify potential strategies for…
The pandemic is stressful for many.
In response to stress, glucocorticoids are released.
They play essential roles as endogenous hormones and clinically as drugs.
High levels are associated with cardiometabolic disorders and with aging.
In contrast, diets like caloric restriction ameliorate metabolic dysfunction and prolong lifespan.
These diets, however, also increase glucocorticoids.
Now the open question is:
What are the molecular and physiological effects of increased hormone levels, and are…
TECHNISCHE UNIVERSITAET MUENCHEN
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