CORDIS Project
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The project focuses on developing efficient synthetic methods for creating 1,3-polyols, which are biologically significant molecules. By merging established chemical techniques, it aims to achieve precise control over the stereochemistry of these compounds, ultimately leading to the synthesis of complex natural product…
An attractive approach to preparing molecules with common repeat units is iterative synthesis, an approach that is extensively used by Nature in the synthesis of large biomolecules.
Nature also uses this tactic for small-molecule synthesis even though common repeat units are not always immediately apparent, the archetypical example being polyketide synthesis.
In contrast, iterative strategies in chemical synthesis are often much less efficient requiring several functional-group interconversions…
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