CORDIS Project
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This project aims to develop methods for analyzing small non-coding RNAs involved in DNA damage response. It focuses on creating a database of these RNAs to better understand their role in genome integrity and cellular functions.
Water, oxygen, and sunlight are essential to most forms of life, yet they also represent a challenging environment for the genetic material as they drive reactions that lead to damage of DNA.
To ensure cell survival, an elaborate response to DNA damage maintains genome integrity.
Until recently, the DNA damage response (DDR) was described as a wave of protein posttranslational modifications that signal the presence of DNA damage to the cell and mobilize enzymatic repair pathways.
Recently, genom…
UNIVERSITY OF GALWAY
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