CORDIS Project
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This project utilizes Single Molecule Pull-down technology to study the regulation of gamma-tubulin ring complexes, which are crucial for microtubule formation. By analyzing these complexes at a molecular level, it aims to provide insights into their role in cellular processes.
In this project I will use Single Molecule Pull-down (SiMPull) for studying activity and regulation of human gamma-tubulinring complexes (gamma-TuRCs).
Gamma-TuRCs are the main nucleators of microtubule (MT) polymerization.
Additionally, gamma-TuRCs may play a role in modulating MT dynamics.
Regulation of gamma-TuRC activity is key to organizing the dynamic MT arrays needed for essential processes in various cell types.
Progress in understanding gamma-TuRC regulation at the molecular level is cu…
FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)
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