CORDIS Project
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This project investigates the communication between the gut and the brain, focusing on sensory neurons that regulate metabolism. It aims to understand how these neurons affect feeding behavior and glucose metabolism, particularly in the context of obesity, using advanced molecular neuroscience techniques.
Communication between the gut and the brain is essential for metabolic function.
Sensory afferent neurons are key gut-brain connectors that monitor gastrointestinal (GI) tract organs, including the stomach, the duodenum, the liver, and the portal vein area, and thereby critically contribute to systemic energy and glucose homeostasis regulation.
Disruption of this neural gut-brain communication develops in obesity and correlates with overeating, body weight gain, and insulin resistance.
However,…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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