CORDIS Project
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This project aims to enhance understanding of gut immunity in Drosophila, focusing on how gut cells respond to pathogens while tolerating beneficial bacteria. It will utilize genetic tools to explore immune responses and maintain gut homeostasis.
The gut is the major interface between microbes and their animal hosts and constitutes the main entry route for pathogens.
As a consequence gut cells must be armed with efficient immune defenses to combat invasion and colonisation by pathogens.
However, the gut also harbors a flora of commensal bacteria, with potentially beneficial effects for the host, which must be tolerated without a chronic, and harmful, immune response.
In recent years Drosophila has emerged as a powerful model to dissect…
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
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