CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the effects of hypercapnic acidosis on lung injury and repair mechanisms in Acute Respiratory Distress Syndrome. It aims to explore the modulation of the NF-kB pathway to enhance protective effects while minimizing potential delays in tissue recovery.
Acute Respiratory Distress Syndrome and Acute Lung Injury [ALI/ARDS] are devastating diseases, causing over 20,000 deaths annually in the US.
Mechanical ventilation may worsen ALI/ARDS, a process termed Ventilator Induced Lung Injury [VILI].
Hypercapnic acidosis (HA) is a central component of lung ventilatory strategies to minimize VILI, and is a potent biologic agent, exerting a myriad of effects on diverse biologic pathways.
Deliberately induced HA is protective in multiple lung injury models.…
UNIVERSITY OF GALWAY
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
